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OpenCRAVAT

Open Custom Ranked Analysis of Variant Tools
Get started with our documentation or install locally.
Get Started Any Way You Want

Install via pip

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OpenCRAVAT is a versatile tool for variant annotation and analysis. You can easily install it using Python’s package manager, pip. Use the command below to get OpenCRAVAT up and running on your system:

python3 -m pip install open-cravat

Installers

The OpenCRAVAT installer provides a user-friendly setup process, allowing users to easily install the software with a few clicks. It includes all necessary dependencies and offers an intuitive interface for variant annotation and analysis right out of the box.

bioconda

BioConda

Bioconda is a cross-platform package manager and can be used as an alternative to pip when installing OpenCRAVAT.

docker

Docker

OpenCRAVAT is available as a Docker container (with over 50,000 downloads!). All functionality is available in the container, including command-line annotation, high-throughput VCF annotation, and the OpenCRAVAT GUI. Designed for highly parallel annotation in the cloud and incorporation into large bioinformatics pipelines.

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Microsoft Azure

OpenCRAVAT can be easily set up to run in Azure, with modules installed from our store mirror on the Genomic Data Lake.  See our instructions to quickly set up an AMI and use a custom script for importing your preferred annotators.

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AWS

An OpenCRAVAT CloudFormation Template is available to automatically pull an input file from S3, spin up an analysis AMI, and output the annotated results back to S3.

Introduction to OpenCRAVAT
Introduction to OpenCRAVAT